Luzia Kalyne Almeida Moreira Leal is a Associate Professor,Universidade Federal do CearĂ¡,Brazil

Luzia Kalyne Almeida Moreira Leal

Associate Professor

Organizing Committee


Universidade Federal do CearĂ¡


LEAL, Luzia Kalyne Almeida Moreira; VIANA, Glauce s b et al. Vitamin D (VD3) antioxidative and anti-inflammatory activities: Peripheral and central effects.EUROPEAN JOURNAL OF PHARMACOLOGY. , v.879, p.173099 - , 2020.

KAREN, Lopes; IGOR, Cavalcante; RAQUEL, Silva; LEAL, Luzia Kalyne Almeida Moreira et al. BINARY MICELLES (E45S8/F127) FOR QUERCETIN AND GRISEOFULVIN SOLUBILISATION. QUIMICA NOVA, p.1 - 6, 2020.

MARIA, Gonzaga; MATHEUS, Campelo; KATARINA, Saraiva; LEAL, Luzia Kalyne Almeida Moreira et al. Chitosan and Agaricus brasiliensis Polysaccharides Films: A PreliminaryStudy. JOURNAL OF THE BRAZILIAN CHEMICAL SOCIETY. v.31, p.990 - 998, 2020.

LEONOR, Angel-Camilo Karen; ALEXANDER, Guerrero-Vargas Jimmy; DE, CarvalhoEmanuella Feitosa; LEAL, Luzia Kalyne Almeida Moreira et al. Disorders on cardiovascular parameters in rats and in human blood cells caused by Lachesis
acrochorda snake venom. TOXICON. , v.184, p.180 - 191, 2020.

ROCHA, Nogueira Tiago; IGOR, de Mesquita Figueredo; MURILO, Tavares Luna Francisco; LEAL, Luzia Kalyne Almeida Moreira et al. Evaluation of oxidative stability of soybean biodiesel using ethanolic and chloroform extracts of Platymiscium
floribundum as antioxidant. RENEWABLE ENERGY. , v.159, p.767 - 774, 2020.

ARANTES, Mariana; PEIJNENBURG, Ad; HENDRIKSEN, Peter; LEAL, Luzia Kalyne Almeida Moreira et al. In vitro toxicological characterisation of the antifungal compound soybean toxin (SBTX). TOXICOLOGY IN VITRO, v.65, p.104824 - , 2020.

SILVEIRA, Elizama Shirley; RODRIGUES, Naya Lúcia de Castro; MACHADO, Nuno Miguel de Jesus; LEAL, Luzia Kalyne Almeida Moreira et al. Medicinal Plants Containing Coumarin or Essential Oils from the Brazilian Biome May be New Option for Treating Leishmaniasis?. PHARMACOGNOSY REVIEWS. v.14, 2020.

G., Nolêto Isabela R. S.; BRUNO, Iles; S., Alencar Matheus; LEAL, Luzia Kalyne Almeida Moreira et al. Alendronate-induced gastric damage in normoglycemic and hyperglycemic rats is reversed by metformin. EUROPEAN JOURNAL OF
PHARMACOLOGY. , v.856, p.172410 - 172418, 2019.

NAYARA, Aquino; EMERSON, Queiroz; LAURENCE, Marcourt; LEAL, Luzia Kalyne Almeida Moreira et al. Chemical Composition and Anti-Inflammatory Activity of the Decoction from Leaves of a Cultivated Specimen of Myracrodruon urundeuva. JOURNAL OF THE BRAZILIAN CHEMICAL SOCIETY. p.1 - 8, 2019.

S., Silveira Elizama; B., Bezerra Suzana; S., Ávila Kalyane; LEAL, Luzia Kalyne Almeida Moreira et al. Gastrointestinal effects of standardized Brazilian phytomedicine (Arthur de Carvalho Drops®) containing Matricaria recutita, Gentiana lutea and Foeniculum vulgare. PATHOPHYSIOLOGY (AMSTERDAM. PRINT). , v.X, p.X - , 2019.

MAGALHÃES, Rocha Talita; J., Machado Nuno; COSTA, de Sousa João Antonio; LEAL, Luzia Kalyne Almeida Moreira et al. Imidazole alkaloids inhibit the pro-inflammatory mechanisms of human neutrophil and exhibit antiinflammatory properties in vivo. JOURNAL OF PHARMACY AND PHARMACOLOGY. p.1 - 11, 2019.

ALEXANDRE, de Aquino Pedro Everson; GOEBEL, de Souza Tamiris de Fátima; SANTOS, Flávia Almeida; LEAL, Luzia Kalyne Almeida Moreira et al. The Wound Healing Property of N -Methyl-(2 S ,4 R )- trans -4-Hydroxy-L-Proline from Sideroxylon obtusifolium is Related to its Anti-Inflammatory and Antioxidant Actions. Journal of Evidence-Based Integrative Medicine. , v.24, p.2515690X1986516 - , 2019.

DIAS, Katia Cilene Ferreira; ALMEIDA, Jamily Cunha de; LEITÃO, Ana Paula de Azevedo et al. Ethanolic Extract of Erythrina Velutina Willd. Pretreatment Attenuates Schizophrenia-Like Behaviors and Oxidative Parameters in Experimental Animal

LOPES, Amanda a; ROCHA, Talita Magalhães; FREITAS, Lyara Barbosa Nogueira; LEAL, Luzia Kalyne Almeida Moreira et al. Eugenol as a promising molecule for the treatment of dermatitis: antioxidant and anti-inflammatory activities and its nanoformulation. Oxidative Medicine and Cellular Longevity. , v.2018, p.1 - 13, 2018.

VASCONCELOS, Silvânia Maria Mendes de; RIBEIRO, Honório Júnior José Eduardo; HONÓRIO JÚNIOR, José Eduardo et al. Flavonoids: biological activities and therapeutic potential. NATURAL PRODUCT RESEARCH. , v.16, p.1 - 14, 2018.

MORAES, Anaftália Felismino; F., Moreira Filho R. N.; O., Passos C. C.; LEAL, Luzia Kalyne Almeida Moreira et al. Hemocompatibility of 2- N -3,6- O -sulfated chitosan films. JOURNAL OF APPLIED POLYMER SCIENCE, v.135, p.47128 - 47137, 2018.

P., de Araújo Dayane; N., Nogueira Patrícia C.; C., Santos Alan Diego; LEAL, Luzia Kalyne Almeida Moreira et al. Aspidosperma pyrifolium Mart: neuroprotective, antioxidant and anti-inflammatory effects in a Parkinson's
disease model in rats. JOURNAL OF PHARMACY AND PHARMACOLOGY. , v.70, p.787 - 796, 2018.

RODRIGUES, de Sousa Francisca Taciana; SOARES, de Sousa Caren Nádia; COELHO, Ximenes Naiara; LEAL, Luzia Kalyne Almeida Moreira et al. Effects of standard ethanolic extract from Erythrina velutina in acute cerebral ischemia in mice.

M., Moura Carlos T.; J., Batista-Lima Francisco; S., Brito Teresinha; LEAL, Luzia Kalyne Almeida Moreira et al. Inhibitory effects of a standardized extract of Justicia pectoralis in an experimental rat model of airway hyper-responsiveness. JOURNAL OF PHARMACY AND PHARMACOLOGY, v.69, p.722 - 732, 2017.

LEAL, Luzia Kalyne Almeida Moreira; HOLANDA, Silva Aline et al. Justicia pectoralis , a coumarin medicinal plant have potential for the development of antiasthmatic drugs?. Revista Brasileira de Farmacognosia-Brazilian Journal of Pharmacognosy. , v.27, p.794 - 802, 2017.

VIANA, Lima Francisco Arnaldo; PINHEIRO, Joventino Ivan; PINHEIRO, Joventino Francisca; LEAL, Luzia Kalyne Almeida Moreira et al.Neuroprotective Activities of Spirulina platensis in the 6-OHDA Model of Parkinson’s Disease Are Related to Its Anti-Inflammatory Effects. NEUROCHEMICAL RESEARCH. ,v.42, p.3390 - 3400, 2017.

ALMEIDA, Raimundo Rafael de; PESSOA, Otília Deusdenia Loiola; ARAUJO, Tamara Gonçalves de et al. Preliminary Evaluation of Novel Triglyceride-Based Nanocomposites for Biomedical Applications. Journal of the Brazilian Chemical Society (Impresso). , p.1 - 10, 2017.

ALEXANDRE, de Aquino Pedro Everson; ROCHA, Magalhães Talita; DUARTE, Nicolau Lucas Antônio et al. The anti-inflammatory effects of N-methyl-(2S,4R)-trans-4- hydroxy-l-proline from Syderoxylon obtusifolium are related to its inhibition of TNFalpha and inflammatory enzymes. Phytomedicine (Stuttgart). , v.24, p.14 - 23, 2017.

LOUCHARD, Bianca Oliveira; SILVA, Ângelo Roncalli a; LEAL, Luzia Kalyne Almeida Moreira et al. Validation of A High Performance Liquid Chromatography Method to Quantify Thymol in Nanocapsules of Bioactive Essential Oil from Lippia Sidoides.International Journal of Complementary and Alternative Medicine. , v.10, p.1 - 7, 2017.


03/2002 – 03-2006 Ph.D. Pharmacology / Universidade Federal do Ceará, Brazil
                               Dissertation: Contribution to the validation of the medicinal use of
                                Amburana cearensis: pharmacological studies with
                                isokaempferide and amburoside
                               Advisor: Glauce Socorro de Barros Viana
03/1992 – 02 –1995   M.Sc. Pharmacology /Universidade Estadual de Campinas (Campinas/SP/Brazil)
03/1997 – 02-2002     Bachelor Degree in Pharmacy / Universidade Federal do Ceara (Fortaleza/CE/Brazil)


My career objective is the use of fundamental and applied knowledge from multidisciplinary fields such as Pharmacognosy, pre-clinical pharmacology and preclinical toxicology focusing on the development of medicines and others bioactives products including plant extracts and molecules. The research field is mainly in the development of natural bioactive materials and prototype. These materials are evaluated for toxicity and pharmacological effects using experimental models of inflammatory diseases, including neurodegenerative diseases, chronic pain, dermatitis and asthma.


Brazilian Society of Pharmacognosy Award, Brazilian Society of Pharmacognosy, Rio Grande do Norte, Brazil, 2011
- Recipient of a scientific productivity grant from CNPq, since 2010 (currently level PQ-2)
- Honorable mention: International Symposium on Neuroinflammation.
METABOLITICS OF THE ENDOFÍTIC FUNGI Lasiodiplodia theobromae, Fortaleza, Ceará,


Several R&D Projects with Brazilian agencies in the last 10 years, adding up to around 500.000 USD.
- Supervised about 21 master students, 5 Phd students, 3 Pos-doc.
- Speaker at the 2nd World Congress on Toxicology and Applied Pharmacology, November 04 -05/2019, Prague, Czech Republic.
- Member of the committee of Coordination for the Improvement of Higher Education Personnel (CAPES), Brasilia, DF, Brazil, 2017
- Chair of First North-Northeast Symposium of Pharmaceutical Sciences, Fortaleza, Ceará, Brazil, 2017(
- Speaker at the Brazilian Symposium of Medicinal Plants (2010), São Paulo, Brazil
- Speaker at the Brazilian Symposium of Medicinal Plants and X International Congress of Ethnopharmacology (2008), São Paulo, Brazil